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b2ml

Official Full Name
beta-2-microglobulin, like
Organism
Danio rerio
GeneID
791742
Background
Predicted to enable MHC class II protein complex binding activity and peptide antigen binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of T cell activation. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane. Is expressed in blastomere and eye. Human ortholog(s) of this gene implicated in arthritis; immunodeficiency 43; and inflammatory bowel disease. Orthologous to human B2M (beta-2-microglobulin). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
b2m; zgc:64161; wu:fb66f11; wu:fj01f08;

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