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ARHGEF3


Official Full Name
Rho guanine nucleotide exchange factor 3
Organism
Homo sapiens
Gene ID
50650
Background
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
GEF3; STA3; XPLN

Cat.No. Product Name Price
SHW001250 shRNA set against Chicken ARHGEF3 (NM_001030595) Inquiry
SHG071191 shRNA set against Mouse Arhgef3(NM_027871.1) Inquiry
SHH239810 shRNA set against Human ARHGEF3 (NM_019555.2) Inquiry
SHH239814 shRNA set against Mouse ARHGEF3 (NM_027871.1) Inquiry
SHH239818 shRNA set against Rat ARHGEF3 (NM_001106061.1) Inquiry
SHW011144 shRNA set against Danio rerio ARHGEF3 (NM_001082868) Inquiry
Cat.No. Product Name Price
MiUTR3H-12303 ARHGEF3 miRNA 3'UTR clone Inquiry
MiUTR3H-12301 ARHGEF3 miRNA 3'UTR clone Inquiry
MiUTR1M-01651 ARHGEF3 miRNA 3'UTR clone Inquiry
CDFR005835 Rat Arhgef3 cDNA Clone(NM_001106061.1) Inquiry
CDCR029894 Human ARHGEF3 ORF clone (NM_001128615.1) Inquiry
CDFL001416 Mouse Arhgef3 cDNA Clone(NM_027871.1) Inquiry
CDCR029902 Mouse Arhgef3 ORF clone (NM_027871.1) Inquiry
CDCR372863 Rat Arhgef3 ORF Clone(NM_001106061.1) Inquiry
MiUTR3H-12302 ARHGEF3 miRNA 3'UTR clone Inquiry
CDFH001127 Human ARHGEF3 cDNA Clone(NM_001128615.1) Inquiry
CDFH001126 Human ARHGEF3 cDNA Clone(NM_001128616.1) Inquiry
CDCS407855 Human ARHGEF3 ORF Clone (BC099715) Inquiry
CDCR029896 Human ARHGEF3 ORF clone (NM_001128616.1) Inquiry
CDCB186335 Rabbit ARHGEF3 ORF clone (XM_008260824.1) Inquiry
CDCB172619 Danio rerio ARHGEF3 ORF Clone (NM_001082868) Inquiry
CDCB162725 Chicken ARHGEF3 ORF Clone (NM_001030595) Inquiry
CDCS407856 Human ARHGEF3 ORF Clone (BC054345) Inquiry
CDCB157663 Human ARHGEF3 ORF clone (BC054345) Inquiry
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