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APLP2


Official Full Name
amyloid beta precursor like protein 2
Organism
Homo sapiens
Gene ID
334
Background
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Synonyms
APPH; APPL2; CDEBP; APLP-2

Cat.No. Product Name Price
SHG065100 shRNA set against Mouse Aplp2(NM_009691.2) Inquiry
SHH238306 shRNA set against Human APLP2 (NM_001642.2) Inquiry
SHH238310 shRNA set against Mouse APLP2 (NM_009691.2) Inquiry
SHW000404 shRNA set against Chicken APLP2 (NM_001006317) Inquiry
SHW012505 shRNA set against Danio rerio APLP2 (NM_001123012) Inquiry
Cat.No. Product Name Price
MiUTR3H-00137 APLP2 miRNA 3'UTR clone Inquiry
MiUTR3H-00135 APLP2 miRNA 3'UTR clone Inquiry
MiUTR3H-00134 APLP2 miRNA 3'UTR clone Inquiry
MiUTR1M-01573 APLP2 miRNA 3'UTR clone Inquiry
CDFH000966 Human APLP2 cDNA Clone(NM_001142278.1) Inquiry
CDFH000965 Human APLP2 cDNA Clone(NM_001142277.1) Inquiry
CDCR028832 Mouse Aplp2 ORF clone (NM_009691.2) Inquiry
CDFH000964 Human APLP2 cDNA Clone(NM_001142276.1) Inquiry
CDCS408239 Human APLP2 ORF Clone (BC000373) Inquiry
MiUTR3H-00136 APLP2 miRNA 3'UTR clone Inquiry
CDCS408238 Human APLP2 ORF Clone (BC004371) Inquiry
CDCR028834 Mouse Aplp2 ORF clone (NM_001102455.1) Inquiry
CDCR028828 Human APLP2 ORF clone (NM_001142278.1) Inquiry
CDCR028826 Human APLP2 ORF clone (NM_001142277.1) Inquiry
CDCR028824 Human APLP2 ORF clone (NM_001142276.1) Inquiry
CDCB182969 Rabbit APLP2 ORF clone (XM_008266796.1) Inquiry
CDCB173980 Danio rerio APLP2 ORF Clone (NM_001123012) Inquiry
CDCR235967 Mouse Aplp2 ORF Clone(NM_001102456.1) Inquiry
CDCB161879 Chicken APLP2 ORF Clone (NM_001006317) Inquiry
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