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ALAD


Official Full Name
aminolevulinate dehydratase
Organism
Homo sapiens
Gene ID
210
Background
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Synonyms
PBGS; ALADH

Cat.No. Product Name Price
SHG051847 shRNA set against Mouse Alad(NM_008525.3) Inquiry
SHW004439 shRNA set against Chicken ALAD (NM_001291406) Inquiry
SHG051883 shRNA set against Rat Alad(NM_012899.2) Inquiry
SHH234706 shRNA set against Human ALAD (NM_000031.5) Inquiry
SHH234710 shRNA set against Mouse ALAD (NM_008525.3) Inquiry
SHH234714 shRNA set against Rat ALAD (NM_012899.2) Inquiry
SHW008299 shRNA set against Danio rerio ALAD (NM_001017645) Inquiry
Cat.No. Product Name Price
CDFR010754 Rat Alad cDNA Clone(NM_012899.2) Inquiry
MiUTR1M-01386 ALAD miRNA 3'UTR clone Inquiry
MiUTR1R-00212 ALAD miRNA 3'UTR clone Inquiry
CDCB165914 Chicken ALAD ORF Clone (NM_001291406) Inquiry
CDCB169774 Danio rerio ALAD ORF Clone (NM_001017645) Inquiry
CDCB184234 Rabbit ALAD ORF clone (XM_002720421.2) Inquiry
CDCR026490 Mouse Alad ORF clone (NM_008525.3) Inquiry
CDCR377757 Rat Alad ORF Clone(NM_012899.2) Inquiry
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