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Agtr1a


Official Full Name
angiotensin II receptor, type 1a
Organism
Mus musculus
Gene ID
11607
Background
Enables angiotensin type I receptor activity. Involved in gene expression; positive regulation of cytokine production; and regulation of blood pressure. Acts upstream of or within several processes, including circulatory system development; regulation of blood pressure; and regulation of smooth muscle cell apoptotic process. Located in endosome and plasma membrane. Is expressed in several structures, including central nervous system; endocrine gland; extraembryonic component; metanephros; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; artery disease (multiple); chronic kidney disease; neurodegenerative disease (multiple); and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Agtr1a; AT1; AG2S; AT1a; AT2R1; Agtr1; AT2R1A; Agt1ar; Agtr-1a; Angtr-1a; 1810074K20Rik

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