Pages
Products

ATP6V0A4


Official Full Name
ATPase H+ transporting V0 subunit a4
Organism
Homo sapiens
Gene ID
50617
Background
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. [provided by RefSeq, Jul 2008]
Synonyms
A4; STV1; VPH1; VPP2; DRTA3; RTA1C; RTADR; ATP6N2; RDRTA2; ATP6N1B

Cat.No. Product Name Price
SHH243002 shRNA set against Human ATP6V0A4 (NM_020632.2) Inquiry
SHH243006 shRNA set against Mouse ATP6V0A4 (NM_080467.3) Inquiry
SHH243010 shRNA set against Rat ATP6V0A4 (NM_001106591.1) Inquiry
SHW002541 shRNA set against Chicken ATP6V0A4 (NM_001080102) Inquiry
Cat.No. Product Name Price
CDFG007634 Human ATP6V0A4 cDNA Clone(NM_130841.2) Inquiry
CDFR006344 Rat Atp6v0a4 cDNA Clone(NM_001106591.1) Inquiry
MiUTR1H-00708 ATP6V0A4 miRNA 3'UTR clone Inquiry
MiUTR3H-07505 ATP6V0A4 miRNA 3'UTR clone Inquiry
MiUTR3H-07506 ATP6V0A4 miRNA 3'UTR clone Inquiry
CDCB164016 Chicken ATP6V0A4 ORF Clone (NM_001080102) Inquiry
CDCB189284 Rabbit ATP6V0A4 ORF clone (XM_008251090.1) Inquiry
CDCR264850 Mouse Atp6v0a4 ORF Clone(NM_080467.3) Inquiry
CDCR315857 Human ATP6V0A4 ORF Clone(NM_130840.2) Inquiry
CDCR315859 Human ATP6V0A4 ORF Clone(NM_130841.2) Inquiry
CDCR373374 Rat Atp6v0a4 ORF Clone(NM_001106591.1) Inquiry
CDCS415112 Human ATP6V0A4 ORF Clone (BC109305) Inquiry
Quick Inquiry