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ASXL3


Official Full Name
ASXL transcriptional regulator 3
Organism
Homo sapiens
Gene ID
80816
Background
This gene encodes a protein containing a plant homeodomain (PHD) zinc finger domain that plays a role in the regulation of gene transcription. The encoded protein has been shown to negatively regulate lipogenesis by binding to and inhibiting the transcriptional activity of two nuclear hormone receptors, oxysterols receptor LXR-alpha (LXRalpha) and thyroid hormone receptor beta (TRbeta). The encoded protein may also inhibit histone deubiquitination. Mutations in this gene have been identified in human patients with Bainbridge-Ropers syndrome, which is characterized by feeding difficulties, developmental delay and other features. [provided by RefSeq, May 2017]
Synonyms
BRPS; KIAA1713

Cat.No. Product Name Price
SHH241770 shRNA set against Human ASXL3 (NM_030632.1) Inquiry
SHH241774 shRNA set against Mouse ASXL3 (NM_001167777.1) Inquiry
Cat.No. Product Name Price
CDCR310482 Human ASXL3 ORF Clone(NM_030632.1) Inquiry
CDFG001660 Human ASXL3 cDNA Clone(NM_030632.1) Inquiry
CDFG021023 Mouse Asxl3 cDNA Clone(NM_001167777.1) Inquiry
MiUTR3H-13671 ASXL3 miRNA 3'UTR clone Inquiry
CDCB187494 Rabbit ASXL3 ORF clone (XM_008261190.1) Inquiry
CDCR241591 Mouse Asxl3 ORF Clone(NM_001167777.1) Inquiry
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