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ARFGEF2

Official Full Name
ARF guanine nucleotide exchange factor 2
Organism
Homo sapiens
GeneID
10564
Background
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Synonyms
BIG2; PVNH2; dJ1164I10.1;

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