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APEH


Official Full Name
acylaminoacyl-peptide hydrolase
Organism
Homo sapiens
Gene ID
327
Background
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008]
Synonyms
APH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2

Cat.No. Product Name Price
SHG064357 shRNA set against Rat Apeh(NM_012500.1) Inquiry
SHG064375 shRNA set against Human APEH(NM_001640.3) Inquiry
SHH238162 shRNA set against Human APEH (NM_001640.3) Inquiry
SHH238166 shRNA set against Mouse APEH (NM_146226.2) Inquiry
SHH238170 shRNA set against Rat APEH (NM_012500.1) Inquiry
SHW001240 shRNA set against Chicken APEH (NM_001030585) Inquiry
SHW015746 shRNA set against Danio rerio APEH (NM_198869) Inquiry
Cat.No. Product Name Price
CDCB177221 Danio rerio APEH ORF Clone (NM_198869) Inquiry
CDCL182720 Human APEH ORF clone(NM_001640.3) Inquiry
CDFH000947 Human APEH cDNA Clone(NM_001640.3) Inquiry
CDFH000948 Human APEH cDNA Clone(NM_001640.3) Inquiry
CDFH000949 Human APEH cDNA Clone(NM_001640.3) Inquiry
CDFH000950 Human APEH cDNA Clone(NM_001640.3) Inquiry
CDFR010178 Rat Apeh cDNA Clone(NM_012500.1) Inquiry
MiUTR1H-00463 APEH miRNA 3'UTR clone Inquiry
MiUTR1R-00297 APEH miRNA 3'UTR clone Inquiry
CDCB162715 Chicken APEH ORF Clone (NM_001030585) Inquiry
CDCB185467 Rabbit APEH ORF clone (XM_002713192.2) Inquiry
CDCR028744 Mouse Apeh ORF clone (NM_146226.2) Inquiry
CDCR377409 Rat Apeh ORF Clone(NM_012500.1) Inquiry
CDCS410354 Human APEH ORF Clone (BC000362) Inquiry
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