Pages
Products

APC


Official Full Name
APC regulator of WNT signaling pathway
Organism
Homo sapiens
Gene ID
324
Background
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers, where disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jun 2022]
Synonyms
GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46

Cat.No. Product Name Price
SHG064045 shRNA set against Mouse Apc(NM_007462.3) Inquiry
SHG064099 shRNA set against Rat Apc(NM_012499.1) Inquiry
SHH238106 shRNA set against Human APC (NM_000038.5) Inquiry
SHH238110 shRNA set against Mouse APC (NM_007462.3) Inquiry
SHH238114 shRNA set against Rat APC (NM_012499.1) Inquiry
SHW013146 shRNA set against Danio rerio APC (NM_001143840) Inquiry
Cat.No. Product Name Price
CDFR010177 Rat Apc cDNA Clone(NM_012499.1) Inquiry
MiUTR1M-01565 APC miRNA 3'UTR clone Inquiry
MiUTR1R-00295 APC miRNA 3'UTR clone Inquiry
CDCB174621 Danio rerio APC ORF Clone (NM_001143840) Inquiry
CDCB185543 Rabbit APC ORF clone (XM_008248399.1) Inquiry
CDCR243638 Mouse Apc ORF Clone(NM_007462.3) Inquiry
CDCR377408 Rat Apc ORF Clone(NM_012499.1) Inquiry
Quick Inquiry