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APBB1


Official Full Name
amyloid beta precursor protein binding family B member 1
Organism
Homo sapiens
Gene ID
322
Background
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Synonyms
RIR; FE65; MGC:9072

Cat.No. Product Name Price
SHG032545 shRNA set against Rat Apbb1(NM_080478.1) Inquiry
SHG032599 shRNA set against Human APBB1(NM_145689.1) Inquiry
SHH238058 shRNA set against Mouse APBB1 (NM_009685.3) Inquiry
SHH238062 shRNA set against Rat APBB1 (NM_080478.1) Inquiry
Cat.No. Product Name Price
CDFG009063 Human APBB1 cDNA Clone(NM_145689.1) Inquiry
CDFR013469 Rat Apbb1 cDNA Clone(NM_080478.1) Inquiry
MiUTR1H-00455 APBB1 miRNA 3'UTR clone Inquiry
MiUTR1R-00293 APBB1 miRNA 3'UTR clone Inquiry
MiUTR3H-05251 APBB1 miRNA 3'UTR clone Inquiry
CDCB156237 Cynomolgus APBB1 ORF clone (XM_005578803.1) Inquiry
CDCB185439 Rabbit APBB1 ORF clone (XM_008265245.1) Inquiry
CDCH015931 Mouse APBB1 ORF clone(NM_001253887.1) Inquiry
CDCH015932 Mouse APBB1 ORF clone(NM_001253885.1) Inquiry
CDCH015933 Mouse APBB1 ORF clone(NM_001253886.1) Inquiry
CDCR028672 Human APBB1 ORF clone (NM_145689.1) Inquiry
CDCR247674 Mouse Apbb1 ORF Clone(NM_009685.3) Inquiry
CDCR380686 Rat Apbb1 ORF Clone(NM_080478.1) Inquiry
CDCS408737 Human APBB1 ORF Clone (BC010854) Inquiry
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