Pages
Products

ANPEP


Official Full Name
alanyl aminopeptidase, membrane
Organism
Homo sapiens
Gene ID
290
Background
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr 2020]
Synonyms
APN; AP-M; AP-N; CD13; LAP1; P150; PEPN; hAPN; GP150

Cat.No. Product Name Price
AD01099Z Human ANPEP adenoviral particles Inquiry
Cat.No. Product Name Price
SHG056143 shRNA set against Rat Anpep(NM_031012.1) Inquiry
SHG056179 shRNA set against Human ANPEP(NM_001150.2) Inquiry
SHH237442 shRNA set against Human ANPEP (NM_001150.2) Inquiry
SHH237446 shRNA set against Mouse ANPEP (NM_008486.2) Inquiry
SHH237450 shRNA set against Rat ANPEP (NM_031012.1) Inquiry
SHW005367 shRNA set against Chicken ANPEP (NM_204861) Inquiry
Cat.No. Product Name Price
CDCL182703 Human ANPEP ORF clone(NM_001150.2) Inquiry
CDFR012488 Rat Anpep cDNA Clone(NM_031012.1) Inquiry
MiUTR1H-00419 ANPEP miRNA 3'UTR clone Inquiry
MiUTR1R-00271 ANPEP miRNA 3'UTR clone Inquiry
CDCB166842 Chicken ANPEP ORF Clone (NM_204861) Inquiry
CDCB180321 Rabbit ANPEP ORF clone (NM_001082326.1) Inquiry
CDCR379510 Rat Anpep ORF Clone(NM_031012.1) Inquiry
Quick Inquiry