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ALPL


Official Full Name
alkaline phosphatase, biomineralization associated
Organism
Homo sapiens
Gene ID
249
Background
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Synonyms
HOPS; HPPA; HPPC; HPPI; HPPO; TNAP; TNALP; APTNAP; TNSALP; AP-TNAP; TNS-ALP

Cat.No. Product Name Price
SHH235478 shRNA set against Mouse ALPL (NM_007431.2) Inquiry
SHG054559 shRNA set against Rat Alpl(NM_013059.1) Inquiry
SHH235474 shRNA set against Human ALPL (NM_000478.4) Inquiry
SHH235482 shRNA set against Rat ALPL (NM_013059.1) Inquiry
SHW005855 shRNA set against Chicken ALPL (NM_205360) Inquiry
SHW017126 shRNA set against Danio rerio ALPL (NM_201007) Inquiry
Cat.No. Product Name Price
CDCH015534 Mouse ALPL ORF clone(NM_007431.2) Inquiry
CDCS405684 Human ALPL ORF Clone (BC110909) Inquiry
CDFH000692 Human ALPL cDNA Clone(NM_001177520.1) Inquiry
CDFR010862 Rat Alpl cDNA Clone(NM_013059.1) Inquiry
MiUTR1M-01371 ALPL miRNA 3'UTR clone Inquiry
MiUTR1R-00239 ALPL miRNA 3'UTR clone Inquiry
MiUTR3H-01716 ALPL miRNA 3'UTR clone Inquiry
MiUTR3H-01717 ALPL miRNA 3'UTR clone Inquiry
CDCB167330 Chicken ALPL ORF Clone (NM_205360) Inquiry
CDCB178601 Danio rerio ALPL ORF Clone (NM_201007) Inquiry
CDCB192972 Rabbit ALPL ORF clone (XM_008265733.1) Inquiry
CDCL182669 Human ALPL ORF clone(NM_000478.4) Inquiry
CDCR026968 Human ALPL ORF clone (NM_001127501.2) Inquiry
CDCR026970 Human ALPL ORF clone (NM_001177520.1) Inquiry
CDCR377939 Rat Alpl ORF Clone(NM_013059.1) Inquiry
CDCS405683 Human ALPL ORF Clone (BC066116) Inquiry
Cat.No. Product Name Price
CC-118 ALPL Easy KO Kit Inquiry
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