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FLT3LG


Official Full Name
fms related receptor tyrosine kinase 3 ligand
Organism
Homo sapiens
Gene ID
2323
Background
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
Synonyms
FL; FLG3L; FLT3L; IMD125

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