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zic2a


Official Full Name
zic family member 2 (odd-paired homolog, Drosophila), a
Organism
Danio rerio
Gene ID
58077
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and regulation of signal transduction. Predicted to be active in nucleus. Is expressed in several structures, including anterior neural keel; central nervous system; ectoderm; neural plate; and presumptive structure. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 5. Orthologous to human ZIC2 (Zic family member 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
zic2; cb851; zic2.1; fb26a03; wu:fb26a03

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