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wasb


Official Full Name
WASP actin nucleation promoting factor b
Organism
Danio rerio
Gene ID
335158
Background
Predicted to enable small GTPase binding activity. Acts upstream of or within leukocyte chemotaxis; myoblast fusion; and regulation of neutrophil migration. Predicted to be located in cytoskeleton and nucleus. Predicted to be active in cytoplasm. Is expressed in hematopoietic system; leukocyte; neuromast; thrombocyte; and thymus. Used to study Wiskott-Aldrich syndrome. Human ortholog(s) of this gene implicated in Wiskott-Aldrich syndrome; X-linked severe congenital neutropenia; and thrombocytopenia. Orthologous to human WAS (WASP actin nucleation promoting factor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
was; zgc:64164; wu:fk81c08

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