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tpma


Official Full Name
alpha-tropomyosin
Organism
Danio rerio
Gene ID
30324
Background
Predicted to enable actin filament binding activity; protein heterodimerization activity; and protein homodimerization activity. Acts upstream of or within myeloid cell development. Predicted to be located in actin cytoskeleton. Predicted to be active in actin filament. Is expressed in adaxial cell; male organism; musculature system; pericardial region; and somite. Human ortholog(s) of this gene implicated in congenital myopathy 4A; dilated cardiomyopathy 1Y; familial hypertrophic cardiomyopathy; hypertrophic cardiomyopathy 3; and nemaline myopathy 1. Orthologous to several human genes including TPM1 (tropomyosin 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
tm; TPM1; fb37a09; wu:fb37a09

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