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smad3a


Official Full Name
SMAD family member 3a
Organism
Danio rerio
Gene ID
58092
Background
Enables sequence-specific DNA binding activity. Acts upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Predicted to be part of heteromeric SMAD protein complex. Is expressed in heart; immature eye; integument; somite; and tail bud. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 3; Lynch syndrome; and pancreatic cancer. Orthologous to human SMAD3 (SMAD family member 3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
madh3; smad3; madh3a; wu:fa99e03

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