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RPSA


Official Full Name
ribosomal protein SA
Organism
Homo sapiens
Gene ID
3921
Background
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
SA; LBP; LRP; p40; uS2; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4

Cat.No. Product Name Price
SHH399700 shRNA set against Mouse RPSA (NM_011029.4) Inquiry
SHH399704 shRNA set against Rat RPSA (NM_017138.2) Inquiry
SHR198222 shRNA set against Human RPSA(NM_001012321.1) Inquiry
SHR198318 shRNA set against Human RPSA(NM_002295.4) Inquiry
SHW000691 shRNA set against Chicken RPSA (NM_001007823) Inquiry
SHW017166 shRNA set against Danio rerio RPSA (NM_201052) Inquiry
Cat.No. Product Name Price
CDCB156417 Rat RPSA ORF clone (BC060578.1) Inquiry
CDCB178641 Danio rerio RPSA ORF Clone (NM_201052) Inquiry
CDCR249490 Mouse Rpsa ORF Clone(NM_011029.4) Inquiry
CDCS419434 Human RPSA ORF Clone (BC066941) Inquiry
CDFH016705 Human RPSA cDNA Clone(NM_001012321.1) Inquiry
CDFH016706 Human RPSA cDNA Clone(NM_002295.4) Inquiry
MiUTR1H-09036 RPSA miRNA 3'UTR clone Inquiry
MiUTR1H-09037 RPSA miRNA 3'UTR clone Inquiry
CDCB162166 Chicken RPSA ORF Clone (NM_001007823) Inquiry
CDCB182283 Rabbit RPSA ORF clone (XM_002713098.2) Inquiry
CDCH075778 human RPSA ORF clone (NM_001012321.1) Inquiry
CDCR282894 Human RPSA ORF Clone(NM_002295.4) Inquiry
CDCR378205 Rat Rpsa ORF Clone(NM_017138.2) Inquiry
CDCS419432 Human RPSA ORF Clone (BC005391) Inquiry
CDCS419433 Human RPSA ORF Clone (BC013827) Inquiry
CDCS419435 Human RPSA ORF Clone (BC050688) Inquiry
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