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Ren1


Official Full Name
renin 1 structural
Organism
Mus musculus
Gene ID
19701
Background
Enables aspartic-type endopeptidase activity. Involved in angiotensin maturation; male gonad development; and mesonephros development. Acts upstream of or within with a positive effect on regulation of blood pressure. Acts upstream of or within several processes, including drinking behavior; hormone-mediated signaling pathway; and renin-angiotensin regulation of aldosterone production. Located in extracellular space. Is active in extracellular region. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Ren1; Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d

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