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RBL1


Official Full Name
RB transcriptional corepressor like 1
Organism
Homo sapiens
Gene ID
5933
Background
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
PRB1; p107; CP107

Cat.No. Product Name Price
SHH390464 shRNA set against Human RBL1 (NM_002895.2) Inquiry
SHR137022 shRNA set against Human RBL1(NM_183404.1) Inquiry
SHR137076 shRNA set against Human RBL1(NM_002895.2) Inquiry
SHW012978 shRNA set against Danio rerio RBL1 (NM_001130610) Inquiry
Cat.No. Product Name Price
CDFG012436 Human RBL1 cDNA Clone(NM_183404.1) Inquiry
CDFH016004 Human RBL1 cDNA Clone(NM_002895.2) Inquiry
MiUTR1H-08675 RBL1 miRNA 3'UTR clone Inquiry
MiUTR3H-00405 RBL1 miRNA 3'UTR clone Inquiry
CDCB174453 Danio rerio RBL1 ORF Clone (NM_001130610) Inquiry
CDCB192270 Rabbit RBL1 ORF clone (XM_008256022.1) Inquiry
CDCR284345 Human RBL1 ORF Clone(NM_002895.2) Inquiry
CDCR325025 Human RBL1 ORF Clone(NM_183404.1) Inquiry
CDCS411027 Human RBL1 ORF Clone (BC032247) Inquiry
CDCS419364 Human RBL1 ORF Clone (BC141917) Inquiry
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