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ptpn2b


Official Full Name
protein tyrosine phosphatase non-receptor type 2b
Organism
Danio rerio
Gene ID
561613
Background
Predicted to enable non-membrane spanning protein tyrosine phosphatase activity and protein kinase binding activity. Predicted to be involved in negative regulation of ERK1 and ERK2 cascade and negative regulation of receptor signaling pathway via JAK-STAT. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including EVL; anterior axial hypoblast; hatching gland; mesoderm; and vasculature. Orthologous to human PTPN2 (protein tyrosine phosphatase non-receptor type 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
cb806; ptpn2; PTP-1B; ptpn2l; zgc:55339; zgc:76973; wu:fc10h07

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