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ptk2ab


Official Full Name
protein tyrosine kinase 2ab
Organism
Danio rerio
Gene ID
142986
Background
Predicted to enable ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in regulation of convergent extension involved in gastrulation. Acts upstream of or within with a positive effect on midbrain-hindbrain boundary morphogenesis. Acts upstream of or within lens fiber cell morphogenesis and regulation of protein localization. Predicted to be located in several cellular components, including cytoskeleton; focal adhesion; and plasma membrane. Is expressed in eye; notochord; segmental plate; somite; and vertical myoseptum. Human ortholog(s) of this gene implicated in leiomyoma; lung small cell carcinoma; and pulmonary hypertension. Orthologous to human PTK2 (protein tyrosine kinase 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
fak; ptk2; fak1a; ptk2a; ptk2.1; zgc:66114; wu:fa18c04

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