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prrx1a


Official Full Name
paired related homeobox 1a
Organism
Danio rerio
Gene ID
406431
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including atrial cardiac muscle cell action potential; epithelial to mesenchymal transition; and heart looping. Predicted to be active in nucleus. Is expressed in several structures, including cranial vault; fin; gill; mesenchyme; and mesoderm. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to human PRRX1 (paired related homeobox 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
pmx1; cb329; prrx1; zgc:64055; wu:fa09h05; wu:fb52c01

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