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PROC


Official Full Name
protein C, inactivator of coagulation factors Va and VIIIa
Organism
Homo sapiens
Gene ID
5624
Background
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]
Synonyms
PC; APC; PROC1; THPH3; THPH4

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CDCR377663 Rat Proc ORF Clone(NM_012803.1) Inquiry
CDCS405572 Human PROC ORF Clone (BC034377) Inquiry
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