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pou5f3


Official Full Name
POU domain, class 5, transcription factor 3
Organism
Danio rerio
Gene ID
30333
Background
Enables several functions, including DNA-binding transcription factor activity; chromatin binding activity; and protein heterodimerization activity. Involved in nucleosome organization. Acts upstream of with a positive effect on cell dedifferentiation. Acts upstream of or within several processes, including brain development; embryonic morphogenesis; and regulation of gene expression. Predicted to be located in nucleus. Is expressed in several structures, including blastoderm; blastodisc; ectoderm; gonad; and hindbrain neural keel. Human ortholog(s) of this gene implicated in embryonal carcinoma and seminoma. Orthologous to human POU5F1 (POU class 5 homeobox 1); POU5F1B (POU class 5 homeobox 1B); and POU5F2 (POU domain class 5, transcription factor 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
gp9; spg; gp-9; oct4; pou2; POU-2; cb197; pou5f1; spg/pou2; chunp6868; wu:fd18d06; etID49452.21

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