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POLG


Official Full Name
DNA polymerase gamma, catalytic subunit
Organism
Homo sapiens
Gene ID
5428
Background
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B

Cat.No. Product Name Price
SHH379216 shRNA set against Mouse POLG (NM_017462.2) Inquiry
SHH379212 shRNA set against Human POLG (NM_002693.2) Inquiry
SHH379220 shRNA set against Rat POLG (NM_053528.1) Inquiry
SHR126720 shRNA set against Mouse Polg(NM_017462.2) Inquiry
SHR126812 shRNA set against Rat Polg(NM_053528.1) Inquiry
Cat.No. Product Name Price
CDCR348320 Human POLG ORF Clone(NM_001126131.1) Inquiry
CDFH014668 Human POLG cDNA Clone(NM_001126131.1) Inquiry
CDFL010527 Mouse Polg cDNA Clone(NM_017462.2) Inquiry
CDFR013253 Rat Polg cDNA Clone(NM_053528.1) Inquiry
MiUTR1M-09393 POLG miRNA 3'UTR clone Inquiry
MiUTR1R-05951 POLG miRNA 3'UTR clone Inquiry
MiUTR3H-01791 POLG miRNA 3'UTR clone Inquiry
MiUTR3H-01792 POLG miRNA 3'UTR clone Inquiry
CDCB189195 Rabbit POLG ORF clone (XM_008275348.1) Inquiry
CDCH065802 Mouse Polg ORF clone (NM_017462.2) Inquiry
CDCR380170 Rat Polg ORF Clone(NM_053528.1) Inquiry
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