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PGPEP1


Official Full Name
pyroglutamyl-peptidase I
Organism
Homo sapiens
Gene ID
54858
Background
The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity. [provided by RefSeq, Jul 2016]
Synonyms
PGI; PGP; Pcp; PGPI; PAP-I; PGP-I

Cat.No. Product Name Price
SHH374396 shRNA set against Human PGPEP1 (NM_017712.2) Inquiry
SHR109712 shRNA set against Human PGPEP1(NM_017712.2) Inquiry
SHH374400 shRNA set against Mouse PGPEP1 (NM_023217.4) Inquiry
SHH374404 shRNA set against Rat PGPEP1 (NM_201988.2) Inquiry
SHR109694 shRNA set against Rat Pgpep1(NM_201988.2) Inquiry
SHW008607 shRNA set against Danio rerio PGPEP1 (NM_001020526) Inquiry
Cat.No. Product Name Price
CDFR015302 Rat Pgpep1 cDNA Clone(NM_201988.2) Inquiry
MiUTR1H-07829 PGPEP1 miRNA 3'UTR clone Inquiry
MiUTR1R-05798 PGPEP1 miRNA 3'UTR clone Inquiry
CDCB170082 Danio rerio PGPEP1 ORF Clone (NM_001020526) Inquiry
CDCB187146 Rabbit PGPEP1 ORF clone (XM_002724245.2) Inquiry
CDCR382378 Rat Pgpep1 ORF Clone(NM_201988.2) Inquiry
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