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pdha1a


Official Full Name
pyruvate dehydrogenase E1 subunit alpha 1a
Organism
Danio rerio
Gene ID
406702
Background
Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to act upstream of or within glucose metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Is expressed in several structures, including adaxial cell; alar plate midbrain region; heart tube; musculature system; and pronephric duct. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency and spermatogenic failure 70. Orthologous to several human genes including PDHA1 (pyruvate dehydrogenase E1 subunit alpha 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
pdha1; zgc:73271; zgc:86692; im:6895726; wu:fd18b01; wu:fo96f03

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