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OTULIN


Official Full Name
OTU deubiquitinase with linear linkage specificity
Organism
Homo sapiens
Gene ID
90268
Background
This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016]
Synonyms
GUM; AIPDS; AIPDSA; IMD107; FAM105B

Cat.No. Product Name Price
SHH288961 shRNA set against Human FAM105B (NM_138348.4) Inquiry
SHH288965 shRNA set against Mouse FAM105B (NM_001013792.2) Inquiry
Cat.No. Product Name Price
CDFG007901 Human FAM105B cDNA Clone(NM_138348.4) Inquiry
MiUTR1H-03389 FAM105B miRNA 3'UTR clone Inquiry
MiUTR1M-02134 FAM105B miRNA 3'UTR clone Inquiry
CDCB193801 Rabbit OTULIN ORF clone (XM_008262076.1) Inquiry
CDCG001372 Mouse FAM105B ORF clone(NM_001013792.2) Inquiry
CDCR062346 Human FAM105B ORF clone (NM_138348.4) Inquiry
CDCS418526 Human FAM105B ORF Clone (BC015392) Inquiry
CDCS418527 Human FAM105B ORF Clone (BC007706) Inquiry
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