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or111-7


Official Full Name
neuropilin 1a
Organism
Danio rerio
Gene ID
353246
Background
Enables vascular endothelial growth factor receptor activity. Involved in several processes, including positive regulation of cell migration involved in sprouting angiogenesis; positive regulation of filopodium assembly; and vascular endothelial growth factor receptor signaling pathway. Acts upstream of or within with a positive effect on angiogenesis involved in wound healing and cell activation. Acts upstream of or within several processes, including axon development; circulatory system development; and regulation of neuron projection development. Predicted to be located in membrane. Predicted to be active in axon; focal adhesion; and plasma membrane. Is expressed in several structures, including cardiovascular system; cranial neural crest cell; hematopoietic stem cell; hypochord; and nervous system. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and tetralogy of Fallot. Orthologous to human NRP1 (neuropilin 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
np-1; nrp1; znrp1; npn-1A; zgc:111785; zgc:136674

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