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nr4a2b


Official Full Name
nuclear receptor subfamily 4, group A, member 2b
Organism
Danio rerio
Gene ID
436679
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear glucocorticoid receptor binding activity. Acts upstream of or within dopaminergic neuron differentiation; forebrain neuron development; and neutrophil homeostasis. Predicted to be located in cytoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in basal plate midbrain region; blood; cranial neural crest; nervous system; and neuroblasts. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
ngf1b; nr4a2; nurr1; zgc:92696

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