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nfe2l2a


Official Full Name
nfe2 like bZIP transcription factor 2a
Organism
Danio rerio
Gene ID
360149
Background
Enables protein heterodimerization activity and transcription cis-regulatory region binding activity. Contributes to DNA-binding transcription factor activity. Acts upstream of or within several processes, including cellular response to prostaglandin stimulus; larval feeding behavior; and positive regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including digestive system; female organism; heart; pleuroperitoneal region; and sensory system. Human ortholog(s) of this gene implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; macular degeneration; and tuberculosis. Orthologous to human NFE2L2 (NFE2 like bZIP transcription factor 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Nrf2; nfe2l2; wu:fc15g09; wu:fj67e03

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