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nf2b


Official Full Name
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor b
Organism
Danio rerio
Gene ID
405887
Background
Predicted to enable actin binding activity and integrin binding activity. Predicted to be involved in several processes, including positive regulation of early endosome to late endosome transport; positive regulation of protein localization to early endosome; and regulation of hippo signaling. Predicted to be located in cytoskeleton and membrane. Predicted to be active in several cellular components, including adherens junction; apical part of cell; and filopodium. Used to study choledochal cyst. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); malignant pleural mesothelioma; meningioma (multiple); neurilemmoma; and vestibular schwannomatosis. Orthologous to human NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
nf2; NF2a

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