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NCOA2


Official Full Name
nuclear receptor coactivator 2
Organism
Homo sapiens
Gene ID
10499
Background
The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Synonyms
SRC2; TIF2; GRIP1; KAT13C; NCoA-2; bHLHe75

Cat.No. Product Name Price
SHH350084 shRNA set against Human NCOA2 (NM_006540.2) Inquiry
SHH350088 shRNA set against Mouse NCOA2 (NM_008678.2) Inquiry
SHH350092 shRNA set against Rat NCOA2 (NM_031822.1) Inquiry
SHR000758 shRNA set against Human NCOA2(NM_006540.2) Inquiry
SHR000906 shRNA set against Mouse Ncoa2(NM_001077695.1) Inquiry
SHR000942 shRNA set against Rat Ncoa2(NM_031822.1) Inquiry
SHR000960 shRNA set against Mouse Ncoa2(NM_008678.2) Inquiry
SHW015177 shRNA set against Danio rerio NCOA2 (NM_131777) Inquiry
Cat.No. Product Name Price
CDFH012260 Human NCOA2 cDNA Clone(NM_006540.2) Inquiry
CDFH012261 Human NCOA2 cDNA Clone(NM_006540.2) Inquiry
CDFL008196 Mouse Ncoa2 cDNA Clone(NM_008678.2) Inquiry
CDFR012952 Rat Ncoa2 cDNA Clone(NM_031822.1) Inquiry
MiUTR1H-06688 NCOA2 miRNA 3'UTR clone Inquiry
MiUTR1M-07530 NCOA2 miRNA 3'UTR clone Inquiry
MiUTR1M-07531 NCOA2 miRNA 3'UTR clone Inquiry
MiUTR1R-04135 NCOA2 miRNA 3'UTR clone Inquiry
SKO0085 NCOA2 Validated sgRNA vector Inquiry
CDCB176652 Danio rerio NCOA2 ORF Clone (NM_131777) Inquiry
CDCB188989 Rabbit NCOA2 ORF clone (XM_008255627.1) Inquiry
CDCL136923 Human Ncoa2 ORF clone (NM_001077695.1) Inquiry
CDCL136925 Human Ncoa2 ORF clone (NM_008678.2) Inquiry
CDCR293111 Human NCOA2 ORF Clone(NM_006540.2) Inquiry
CDCR379966 Rat Ncoa2 ORF Clone(NM_031822.1) Inquiry
CDCS412791 Human NCOA2 ORF Clone (BC114383) Inquiry
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