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MOCOS


Official Full Name
molybdenum cofactor sulfurase
Organism
Homo sapiens
Gene ID
55034
Background
This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine. [provided by RefSeq, Apr 2017]
Synonyms
MCS; MOS; HMCS

Cat.No. Product Name Price
SHH195023 shRNA set against Human MOCOS(NM_017947.2) Inquiry
SHH195041 shRNA set against Mouse Mocos(NM_026779.1) Inquiry
SHH343356 shRNA set against Human MOCOS (NM_017947.2) Inquiry
SHH343361 shRNA set against Mouse MOCOS (NM_026779.1) Inquiry
SHH343364 shRNA set against Rat MOCOS (NM_001108425.1) Inquiry
SHW008165 shRNA set against Danio rerio MOCOS (NM_001014366) Inquiry
Cat.No. Product Name Price
CDFR008041 Rat Mocos cDNA Clone(NM_001108425.1) Inquiry
MiUTR1H-06374 MOCOS miRNA 3'UTR clone Inquiry
MiUTR1M-07199 MOCOS miRNA 3'UTR clone Inquiry
CDCB169640 Danio rerio MOCOS ORF Clone (NM_001014366) Inquiry
CDCB185862 Rabbit MOCOS ORF clone (XM_008261215.1) Inquiry
CDCL133367 Human Mocos ORF clone (NM_026779.1) Inquiry
CDCR375082 Rat Mocos ORF Clone(NM_001108425.1) Inquiry
CDCS414577 Human MOCOS ORF Clone (BC012079) Inquiry
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