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MCSFR


Official Full Name
colony stimulating factor 1 receptor
Organism
Homo sapiens
Gene ID
1436
Background
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. [provided by RefSeq, Mar 2017]
Synonyms
CSF1R; FMS; CSFR; FIM2; GPSC; HDLS; C-FMS; CD115; HDLS1; CSF-1R; BANDDOS; M-CSF-R

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AD04263Z Human CSF1R adenoviral particles Inquiry
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SHG202267 shRNA set against Mouse Csf1r(NM_001037859.2) Inquiry
SHG202213 shRNA set against Rat Csf1r(NM_001029901.1) Inquiry
SHH270229 shRNA set against Human CSF1R (NM_005211.3) Inquiry
SHH270233 shRNA set against Rat CSF1R (NM_001029901.1) Inquiry
SHW015086 shRNA set against Danio rerio CSF1RA (NM_131672) Inquiry
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CDCR371150 Rat Csf1r ORF Clone(NM_001029901.1) Inquiry
CDFR004123 Rat Csf1r cDNA Clone(NM_001029901.1) Inquiry
MiUTR1M-03376 CSF1R miRNA 3'UTR clone Inquiry
MiUTR1R-01214 CSF1R miRNA 3'UTR clone Inquiry
MiUTR3H-01600 CSF1R miRNA 3'UTR clone Inquiry
CDCB156492 Canine CSF1R ORF clone (XM_546306.3) Inquiry
CDCB156903 Cynomolgus CSF1R ORF clone Inquiry
CDCB176561 Danio rerio CSF1RA ORF Clone (NM_131672) Inquiry
CDCB193037 Rabbit CSF1R ORF clone (XM_008255253.1) Inquiry
CDCB196052 Rabbit LOC103351148 ORF clone (XM_008269274.1) Inquiry
CDCL185296 Human MCSFR ORF clone(NM_005211.3) Inquiry
CDCL185297 Mouse MCSFR ORF clone(NM_001037859.2) Inquiry
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