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klf6a


Official Full Name
Kruppel like factor 6a
Organism
Danio rerio
Gene ID
280650
Background
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; chromatin binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including erythrocyte maturation; optic nerve formation; and regulation of hematopoietic stem cell migration. Is active in chromatin. Is expressed in several structures, including cardiovascular system; digestive system; intermediate cell mass of mesoderm; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in prostate cancer and stomach cancer. Orthologous to human KLF6 (KLF transcription factor 6). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
klf6; cb538; copeb; wu:fb76d04; wu:fb92h03; wu:fe26g06; wu:fk78f12

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