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keap1a


Official Full Name
kelch-like ECH-associated protein 1a
Organism
Danio rerio
Gene ID
321837
Background
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Acts upstream of or within cellular response to prostaglandin stimulus; cellular response to xenobiotic stimulus; and larval feeding behavior. Predicted to be located in inclusion body. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in gallbladder cancer. Orthologous to human KEAP1 (kelch like ECH associated protein 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
keap1; wu:fb36f11

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