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kdm6bb


Official Full Name
lysine (K)-specific demethylase 6B, b
Organism
Danio rerio
Gene ID
563644
Background
Enables H3K27me3 modified histone binding activity and histone H3K27me2/H3K27me3 demethylase activity. Acts upstream of or within several processes, including common myeloid progenitor cell proliferation; fin regeneration; and primitive erythrocyte differentiation. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. Is expressed in caudal hematopoietic tissue; central nervous system; heart; and otic vesicle. Human ortholog(s) of this gene implicated in Stolerman neurodevelopmental syndrome. Orthologous to human KDM6B (lysine demethylase 6B). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
jmjd3; kdm6b; jmjd3a; zC237L4.7; si:ch211-237l4.7

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