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jam2a


Official Full Name
junctional adhesion molecule 2a
Organism
Danio rerio
Gene ID
100005261
Background
Enables protein heterodimerization activity. Involved in regulation of skeletal muscle fiber development. Acts upstream of or within with a positive effect on myoblast fusion. Acts upstream of or within hematopoietic or lymphoid organ development. Predicted to be located in bicellular tight junction and membrane. Predicted to be part of protein complex involved in cell adhesion. Predicted to be active in cell surface; plasma membrane; and tight junction. Is expressed in several structures, including blood vessel; musculature system; myoblast; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human JAM2 (junctional adhesion molecule 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
jam2; JAM-B; sb:cb1002

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