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IFNΑ R2


Official Full Name
tumor necrosis factor
Organism
Homo sapiens
Gene ID
7124
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020]
Synonyms
TNF; DIF; TNFA; IMD127; TNFSF2; TNLG1F; TNF-alpha

Cat.No. Product Name Price
SHH317129 shRNA set against Human IFNAR2 (NM_000874.3) Inquiry
SHL166814 shRNA set against Mouse Ifnar2(NM_010509.2) Inquiry
SHR174008 shRNA set against Human IFNAR2(NM_000874.3) Inquiry
SHR174570 shRNA set against Human IFNAR2(NM_207585.1) Inquiry
SHW005364 shRNA set against Chicken IFNAR2 (NM_204858) Inquiry
Cat.No. Product Name Price
CDFG013887 Human IFNAR2 cDNA Clone(NM_207585.1) Inquiry
CDFG013888 Human IFNAR2 cDNA Clone(NM_207584.1) Inquiry
CDFG019049 Mouse Ifnar2 cDNA Clone(NM_001110498.1) Inquiry
CDFH009013 Human IFNAR2 cDNA Clone(NM_000874.3) Inquiry
MiUTR1H-04814 IFNAR2 miRNA 3'UTR clone Inquiry
MiUTR1H-04815 IFNAR2 miRNA 3'UTR clone Inquiry
MiUTR1M-05920 IFNAR2 miRNA 3'UTR clone Inquiry
MiUTR3H-04924 IFNAR2 miRNA 3'UTR clone Inquiry
CDCB156766 Cynomolgus IFNAR2 ORF clone Inquiry
CDCB166839 Chicken IFNAR2 ORF Clone (NM_204858) Inquiry
CDCB194752 Rabbit IFNAR2 ORF clone (XM_008274948.1) Inquiry
CDCL119559 Mouse Ifnar2 ORF clone (NM_001110498.1) Inquiry
CDCL184691 Human IFNα R2 ORF clone(NM_207585.1) Inquiry
CDCR328227 Human IFNAR2 ORF Clone(NM_207584.1) Inquiry
CDCR337900 Human IFNAR2 ORF Clone(NM_000874.3) Inquiry
CDCS405965 Human IFNAR2 ORF Clone (BC002793) Inquiry
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