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grapa


Official Full Name
GRB2 related adaptor protein a
Organism
Danio rerio
Gene ID
553596
Background
Predicted to enable epidermal growth factor receptor binding activity and phosphotyrosine residue binding activity. Predicted to be involved in regulation of MAPK cascade and signal transduction. Predicted to be part of COP9 signalosome. Predicted to be active in cytoplasm; nucleoplasm; and plasma membrane. Is expressed in several structures, including eye; optic vesicle; pronephric duct; pronephric mesoderm; and solid lens vesicle. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 114. Orthologous to human GRAP (GRB2 related adaptor protein). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
grap; zgc:110202

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