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Gm98


Official Full Name
myelin regulatory factor
Organism
Mus musculus
Gene ID
225908
Background
Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including central nervous system myelin maintenance; positive regulation of myelination; and regulation of DNA-templated transcription. Located in endoplasmic reticulum membrane and nucleus. Is expressed in pigmented retinal epithelium; spinal cord; and spinal cord marginal layer. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; hyperopia; nanophthalmos; and primary angle-closure glaucoma. Orthologous to human MYRF (myelin regulatory factor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Myrf; Mrf; Gm98; Gm1804; 6030439E18

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