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Fcgr4


Official Full Name
Fc receptor, IgG, low affinity IV
Organism
Mus musculus
Gene ID
246256
Background
Enables IgE receptor activity and IgG receptor activity. Involved in several processes, including Fc receptor-mediated immune complex endocytosis; neutrophil activation; and positive regulation of bone resorption. Located in cell surface and plasma membrane. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); glomerulonephritis (multiple); graft-versus-host disease; and hematologic cancer (multiple). Orthologous to several human genes including FCGR3A (Fc gamma receptor IIIa). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Fcgr4; Fcrl3; CD16-2; FcgRIV; Fcgr3a; FcgammaRIV; 4833442P21Rik

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