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egfra


Official Full Name
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Organism
Danio rerio
Gene ID
378478
Background
Predicted to enable epidermal growth factor binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in regulation of circadian sleep/wake cycle, sleep. Acts upstream of or within blood vessel lumenization. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in basal plasma membrane. Is expressed in several structures, including gill; liver; nervous system; pleuroperitoneal region; and somite. Human ortholog(s) of this gene implicated in several diseases, including colorectal cancer; lung cancer (multiple); pancreatic cancer; prostate cancer; and pulmonary tuberculosis. Orthologous to human EGFR (epidermal growth factor receptor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
egfr; EGFR12; EGFR15

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