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DYTN


Official Full Name
dystrotelin
Organism
Homo sapiens
Gene ID
391475
Background
This gene belongs to the dystrophin superfamily, which is characterized by the presence of four EF-hand motifs and a ZZ-domain. It is a likely ortholog of the Drosophila 'discontinuous actin hexagon' gene. It is noteworthy that the coding region of this gene lacks two coding exons that are found in the mouse ortholog. Human transcripts including these two exons are subject to nonsense-mediated transcript decay (NMD). On the other hand, transcripts skipping the two coding exons are expressed at very low levels. While this gene maintains an intact CDS, it may be an evolving pseudogene. However, after a discussion about this gene within the RefSeq group, as well as in the consensus coding sequence (CCDS) collaboration, it was decided to keep it as a protein-coding gene in the RefSeq, Ensembl-GENCODE and the CCDS sets. [provided by RefSeq, Jul 2019]
Synonyms
flot1; reggie2; wu:fj45g11; si:dz44o19.1

Cat.No. Product Name Price
SHH282349 shRNA set against Human DYTN (NM_001093730.1) Inquiry
SHH282353 shRNA set against Mouse DYTN (NM_001081658.1) Inquiry
SHW010969 shRNA set against Danio rerio DYTN (NM_001080587) Inquiry
Cat.No. Product Name Price
CDFH005569 Human DYTN cDNA Clone(NM_001093730.1) Inquiry
MiUTR1M-05121 DYTN miRNA 3'UTR clone Inquiry
CDCB172444 Danio rerio DYTN ORF Clone (NM_001080587) Inquiry
CDCB188893 Rabbit DYTN ORF clone (XM_002712590.1) Inquiry
CDCR058058 Human DYTN ORF clone (NM_001093730.1) Inquiry
CDCR058060 Mouse Dytn ORF clone (NM_001081658.1) Inquiry
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