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dyrk1aa


Official Full Name
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
Organism
Danio rerio
Gene ID
100005019
Background
Predicted to enable protein serine/threonine kinase activity and transcription coactivator activity. Acts upstream of or within angiogenesis and brain development. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in endothelial cell; heart; nervous system; and pharyngeal arch. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in Down syndrome; autism spectrum disorder; autosomal dominant intellectual developmental disorder 7; and intellectual disability. Orthologous to human DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
dyrk1a; im:6962097; zgc:158359

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