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dvl3a


Official Full Name
dishevelled segment polarity protein 3a
Organism
Danio rerio
Gene ID
80972
Background
Predicted to enable frizzled binding activity. Involved in positive regulation of Wnt signaling pathway, planar cell polarity pathway. Acts upstream of or within canonical Wnt signaling pathway; convergent extension involved in axis elongation; and post-anal tail morphogenesis. Located in cell cortex and spindle. Is expressed in liver and male organism. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 3 and lung cancer. Orthologous to human DVL3 (dishevelled segment polarity protein 3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
dvl3; wu:fb75f04; wu:fi22h02; wu:fp61b09

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