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DAND5


Official Full Name
DAN domain BMP antagonist family member 5
Organism
Homo sapiens
Gene ID
199699
Background
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
Synonyms
SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; HTX13; CKTSF1B3

Cat.No. Product Name Price
SHH274485 shRNA set against Human DAND5 (NM_152654.2) Inquiry
SHH274489 shRNA set against Mouse DAND5 (NM_201227.3) Inquiry
SHW018104 shRNA set against Danio rerio DAND5 (NM_212969) Inquiry
Cat.No. Product Name Price
CDCS418407 Human DAND5 ORF Clone (BC113476) Inquiry
CDFG009663 Human DAND5 cDNA Clone(NM_152654.2) Inquiry
MiUTR1H-02662 DAND5 miRNA 3'UTR clone Inquiry
CDCB179579 Danio rerio DAND5 ORF Clone (NM_212969) Inquiry
CDCB188954 Rabbit DAND5 ORF clone (XM_002724474.2) Inquiry
CDCL183666 Human COCO ORF clone(NM_152654.2) Inquiry
CDCR276925 Mouse Dand5 ORF Clone(NM_201227.3) Inquiry
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